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Glial cells suppress postencephalitic CD8(+) T lymphocytes through PD‐L1

Engagement of the programmed death (PD)−1 receptor on activated cells by its ligand (PD‐L1) is a mechanism for suppression of activated T‐lymphocytes. Microglia, the resident inflammatory cells of the brain, are important for pathogen detection and initiation of innate immunity, however, a novel rol...

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Detalles Bibliográficos
Autores principales: Schachtele, Scott J., Hu, Shuxian, Sheng, Wen S., Mutnal, Manohar B., Lokensgard, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141010/
https://www.ncbi.nlm.nih.gov/pubmed/24890099
http://dx.doi.org/10.1002/glia.22701