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Glial cells suppress postencephalitic CD8(+) T lymphocytes through PD‐L1
Engagement of the programmed death (PD)−1 receptor on activated cells by its ligand (PD‐L1) is a mechanism for suppression of activated T‐lymphocytes. Microglia, the resident inflammatory cells of the brain, are important for pathogen detection and initiation of innate immunity, however, a novel rol...
Autores principales: | Schachtele, Scott J., Hu, Shuxian, Sheng, Wen S., Mutnal, Manohar B., Lokensgard, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141010/ https://www.ncbi.nlm.nih.gov/pubmed/24890099 http://dx.doi.org/10.1002/glia.22701 |
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