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Influence of KIR genes and their HLA ligands in the pathogenesis of leprosy in a hyperendemic population of Rondonópolis, Southern Brazil

BACKGROUND: The objective of this study was to investigate the association between KIR genes and the immunopathogenesis of leprosy. METHODS: The types of KIR and HLA genes were evaluated by PCR-SSOP-Luminex in 408 patients with leprosy and 413 healthy individuals. Statistical analysis was performed...

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Detalles Bibliográficos
Autores principales: Jarduli, Luciana Ribeiro, Alves, Hugo Vicentin, de Souza-Santana, Fabiana Covolo, Marcos, Elaine Valim Camarinha, Pereira, Ana Carla, Dias-Baptista, Ida Maria Foschiani, Fava, Vinícius Medeiros, Mira, Marcelo Távora, Moraes, Milton Ozório, Virmond, Marcos da Cunha Lopes, Visentainer, Jeane Eliete Laguila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141108/
https://www.ncbi.nlm.nih.gov/pubmed/25117794
http://dx.doi.org/10.1186/1471-2334-14-438