The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells

Different from canonical ubiquitin-like proteins, Hub1 does not form covalent conjugates with substrates but binds proteins non-covalently. In Saccharomyces cerevisiae, Hub1 associates with spliceosomes and mediates alternative splicing of SRC1, without affecting pre-mRNA splicing generally. Human H...

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Detalles Bibliográficos
Autores principales: Ammon, Tim, Mishra, Shravan Kumar, Kowalska, Kaja, Popowicz, Grzegorz M., Holak, Tad A., Jentsch, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141198/
https://www.ncbi.nlm.nih.gov/pubmed/24872507
http://dx.doi.org/10.1093/jmcb/mju026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141198/
https://www.ncbi.nlm.nih.gov/pubmed/24872507
http://dx.doi.org/10.1093/jmcb/mju026

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