Mammalian Target of Rapamycin Inhibitors Resistance Mechanisms in Clear Cell Renal Cell Carcinoma

Mammalian target of rapamycin (mTOR) is a kinase protein involved in PI3K/AKT signaling with a central role in the processes of cell growth, survival and angiogenesis. Frequent mutations of this pathway make upstream and downstream components novel targets for tailored therapy design. Two mTOR inhib...

Descripción completa

Detalles Bibliográficos
Autores principales: Kornakiewicz, Anna, Solarek, Wojciech, Bielecka, Zofia F., Lian, Fei, Szczylik, Cezary, Czarnecka, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141323/
https://www.ncbi.nlm.nih.gov/pubmed/25152703
http://dx.doi.org/10.2174/1574362409666140206222746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141323/
https://www.ncbi.nlm.nih.gov/pubmed/25152703
http://dx.doi.org/10.2174/1574362409666140206222746

Ejemplares similares