Motor and cognitive deficits in aged tau knockout mice in two background strains

BACKGROUND: We recently reported that Parkinsonian and dementia phenotypes emerge between 7-12 months of age in tau(-/-) mice on a Bl6/129sv mixed background. These observations were partially replicated by another group using pure Bl6 background tau(-/-) mice, but notably they did not observe a cog...

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Detalles Bibliográficos
Autores principales: Lei, Peng, Ayton, Scott, Moon, Steve, Zhang, Qihao, Volitakis, Irene, Finkelstein, David I, Bush, Ashley I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141346/
https://www.ncbi.nlm.nih.gov/pubmed/25124182
http://dx.doi.org/10.1186/1750-1326-9-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141346/
https://www.ncbi.nlm.nih.gov/pubmed/25124182
http://dx.doi.org/10.1186/1750-1326-9-29

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