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Motor and cognitive deficits in aged tau knockout mice in two background strains
BACKGROUND: We recently reported that Parkinsonian and dementia phenotypes emerge between 7-12 months of age in tau(-/-) mice on a Bl6/129sv mixed background. These observations were partially replicated by another group using pure Bl6 background tau(-/-) mice, but notably they did not observe a cog...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141346/ https://www.ncbi.nlm.nih.gov/pubmed/25124182 http://dx.doi.org/10.1186/1750-1326-9-29 |