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Tissue signatures influence the activation of intrahepatic CD8(+) T cells against malaria sporozoites

Plasmodium sporozoites and liver stages express antigens that are targeted to the MHC-Class I antigen-processing pathway. After the introduction of Plasmodium sporozoites by Anopheles mosquitoes, bone marrow-derived dendritic cells in skin-draining lymph nodes are the first cells to cross-present pa...

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Detalles Bibliográficos
Autores principales: Morrot, Alexandre, Rodrigues, Maurício M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141441/
https://www.ncbi.nlm.nih.gov/pubmed/25202304
http://dx.doi.org/10.3389/fmicb.2014.00440