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Tissue signatures influence the activation of intrahepatic CD8(+) T cells against malaria sporozoites
Plasmodium sporozoites and liver stages express antigens that are targeted to the MHC-Class I antigen-processing pathway. After the introduction of Plasmodium sporozoites by Anopheles mosquitoes, bone marrow-derived dendritic cells in skin-draining lymph nodes are the first cells to cross-present pa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141441/ https://www.ncbi.nlm.nih.gov/pubmed/25202304 http://dx.doi.org/10.3389/fmicb.2014.00440 |