Eukaryotic Initiation Factor 4G Suppresses Nonsense-Mediated mRNA Decay by Two Genetically Separable Mechanisms

Nonsense-mediated mRNA decay (NMD), which is best known for degrading mRNAs with premature termination codons (PTCs), is thought to be triggered by aberrant translation termination at stop codons located in an environment of the mRNP that is devoid of signals necessary for proper termination. In mam...

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Detalles Bibliográficos
Autores principales: Joncourt, Raphael, Eberle, Andrea B., Rufener, Simone C., Mühlemann, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141738/
https://www.ncbi.nlm.nih.gov/pubmed/25148142
http://dx.doi.org/10.1371/journal.pone.0104391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141738/
https://www.ncbi.nlm.nih.gov/pubmed/25148142
http://dx.doi.org/10.1371/journal.pone.0104391

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