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Core structure of the U6 snRNP at 1.7 Å resolution

The spliceosome is a dynamic assembly of five small nuclear ribonucleoproteins (snRNPs) that removes introns from eukaryotic pre-mRNA. U6 is the most conserved of the spliceosomal snRNAs and participates directly in catalysis. Here, we report the crystal structure of the Saccharomyces cerevisiae U6...

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Detalles Bibliográficos
Autores principales: Montemayor, Eric J., Curran, Elizabeth C., Liao, Hong Hong, Andrews, Kristie L., Treba, Christine N., Butcher, Samuel E., Brow, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141773/
https://www.ncbi.nlm.nih.gov/pubmed/24837192
http://dx.doi.org/10.1038/nsmb.2832