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A Meta-Analysis of Multiple Matched Copy Number and Transcriptomics Data Sets for Inferring Gene Regulatory Relationships

Inferring gene regulatory relationships from observational data is challenging. Manipulation and intervention is often required to unravel causal relationships unambiguously. However, gene copy number changes, as they frequently occur in cancer cells, might be considered natural manipulation experim...

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Detalles Bibliográficos
Autores principales: Newton, Richard, Wernisch, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141782/
https://www.ncbi.nlm.nih.gov/pubmed/25148247
http://dx.doi.org/10.1371/journal.pone.0105522