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Sialic Acid Metabolic Engineering: A Potential Strategy for the Neuroblastoma Therapy
BACKGROUND: Sialic acids (Sia) represent negative-charged terminal sugars on most glycoproteins and glycolipids on the cell surface of vertebrates. Aberrant expression of tumor associated sialylated carbohydrate epitopes significantly increases during onset of cancer. Since Sia contribute towards ce...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141789/ https://www.ncbi.nlm.nih.gov/pubmed/25148252 http://dx.doi.org/10.1371/journal.pone.0105403 |