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Sialic Acid Metabolic Engineering: A Potential Strategy for the Neuroblastoma Therapy

BACKGROUND: Sialic acids (Sia) represent negative-charged terminal sugars on most glycoproteins and glycolipids on the cell surface of vertebrates. Aberrant expression of tumor associated sialylated carbohydrate epitopes significantly increases during onset of cancer. Since Sia contribute towards ce...

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Detalles Bibliográficos
Autores principales: Gnanapragassam, Vinayaga S., Bork, Kaya, Galuska, Christina E., Galuska, Sebastian P., Glanz, Dagobert, Nagasundaram, Manimozhi, Bache, Matthias, Vordermark, Dirk, Kohla, Guido, Kannicht, Christoph, Schauer, Roland, Horstkorte, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141789/
https://www.ncbi.nlm.nih.gov/pubmed/25148252
http://dx.doi.org/10.1371/journal.pone.0105403