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Akt2 Is Involved in Loss of Epithelial Cells and Renal Fibrosis following Unilateral Ureteral Obstruction

Obstructive nephropathy is an aggressive form of chronic kidney disease (CKD), which is characterized by an epithelial-to-mesenchymal transition (EMT) and interstitial fibrosis. However, the molecular mechanisms of EMT and fibrosis are complex and not fully understood. In this study, we investigated...

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Detalles Bibliográficos
Autores principales: Lan, Aiping, Zhang, Jing, Xiao, Zhicheng, Peng, Xiaogang, Qi, Yongfen, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141797/
https://www.ncbi.nlm.nih.gov/pubmed/25148525
http://dx.doi.org/10.1371/journal.pone.0105451