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Clusterin/Apolipoprotein J Attenuates Angiotensin II-Induced Renal Fibrosis
The blockade of angiotensin II (Ang II) is a major therapeutic strategy for diabetic nephropathy. The main roles of Ang II in renal disease are mediated via the Ang type 1 receptor (AT1R). Upregulation of clusterin/apolipoprotein J has been reported in nephropathy models, suggesting it has a protect...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141810/ https://www.ncbi.nlm.nih.gov/pubmed/25148511 http://dx.doi.org/10.1371/journal.pone.0105635 |