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DNA Binding Properties of the Small Cascade Subunit Csa5

CRISPR-Cas systems provide immunity against viral attacks in archaeal and bacterial cells. Type I systems employ a Cas protein complex termed Cascade, which utilizes small CRISPR RNAs to detect and degrade the exogenic DNA. A small sequence motif, the PAM, marks the foreign substrates. Previously, a...

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Detalles Bibliográficos
Autores principales: Daume, Michael, Plagens, André, Randau, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141822/
https://www.ncbi.nlm.nih.gov/pubmed/25148031
http://dx.doi.org/10.1371/journal.pone.0105716