Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice

The inhibition of sensory responsivity is considered a core serotonin function, yet this hypothesis lacks direct support due to methodological obstacles. We adapted an optogenetic approach to induce acute, robust and specific firing of dorsal raphe serotonergic neurons. In vitro, the responsiveness...

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Detalles Bibliográficos
Autores principales: Dugué, Guillaume P., Lörincz, Magor L., Lottem, Eran, Audero, Enrica, Matias, Sara, Correia, Patricia A., Léna, Clément, Mainen, Zachary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141837/
https://www.ncbi.nlm.nih.gov/pubmed/25148042
http://dx.doi.org/10.1371/journal.pone.0105941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141837/
https://www.ncbi.nlm.nih.gov/pubmed/25148042
http://dx.doi.org/10.1371/journal.pone.0105941

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