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PredPPCrys: Accurate Prediction of Sequence Cloning, Protein Production, Purification and Crystallization Propensity from Protein Sequences Using Multi-Step Heterogeneous Feature Fusion and Selection

X-ray crystallography is the primary approach to solve the three-dimensional structure of a protein. However, a major bottleneck of this method is the failure of multi-step experimental procedures to yield diffraction-quality crystals, including sequence cloning, protein material production, purific...

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Detalles Bibliográficos
Autores principales: Wang, Huilin, Wang, Mingjun, Tan, Hao, Li, Yuan, Zhang, Ziding, Song, Jiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141844/
https://www.ncbi.nlm.nih.gov/pubmed/25148528
http://dx.doi.org/10.1371/journal.pone.0105902