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Functional Dynamics of Hexameric Helicase Probed by Hydrogen Exchange and Simulation

The biological function of large macromolecular assemblies depends on their structure and their dynamics over a broad range of timescales; for this reason, it is a significant challenge to investigate these assemblies using conventional experimental techniques. One of the most promising experimental...

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Detalles Bibliográficos
Autores principales: Radou, Gaël, Dreyer, Frauke N., Tuma, Roman, Paci, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142241/
https://www.ncbi.nlm.nih.gov/pubmed/25140434
http://dx.doi.org/10.1016/j.bpj.2014.06.039