Structural basis of the alternating-access mechanism in a bile acid transporter

Bile acids are synthesized from cholesterol in hepatocytes and secreted via the biliary tract into the small intestine, where they aid in absorption of lipids and fat-soluble vitamins. Through a process known as enterohepatic recirculation, more than 90% of secreted bile acids are then retrieved fro...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Xiaoming, Levin, Elena J., Pan, Yaping, McCoy, Jason G., Sharma, Ruchika, Kloss, Brian, Bruni, Renato, Quick, Matthias, Zhou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142352/
https://www.ncbi.nlm.nih.gov/pubmed/24317697
http://dx.doi.org/10.1038/nature12811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142352/
https://www.ncbi.nlm.nih.gov/pubmed/24317697
http://dx.doi.org/10.1038/nature12811

Ejemplares similares