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Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy
BACKGROUND: Fibrosis, an excessive collagen accumulation, results in scar formation, impairing function of vital organs and tissues. Fibrosis is a hallmark of muscular dystrophies, including the lethal Duchenne muscular dystrophy (DMD), which remains incurable. Substitution of muscle by fibrotic tis...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142391/ https://www.ncbi.nlm.nih.gov/pubmed/25157321 http://dx.doi.org/10.1186/2044-5040-4-7 |