Cargando…
Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy
BACKGROUND: Fibrosis, an excessive collagen accumulation, results in scar formation, impairing function of vital organs and tissues. Fibrosis is a hallmark of muscular dystrophies, including the lethal Duchenne muscular dystrophy (DMD), which remains incurable. Substitution of muscle by fibrotic tis...
Autores principales: | Pessina, Patrizia, Cabrera, Daniel, Morales, María Gabriela, Riquelme, Cecilia A, Gutiérrez, Jaime, Serrano, Antonio L, Brandan, Enrique, Muñoz-Cánoves, Pura |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142391/ https://www.ncbi.nlm.nih.gov/pubmed/25157321 http://dx.doi.org/10.1186/2044-5040-4-7 |
Ejemplares similares
-
Understanding the Process of Fibrosis in Duchenne Muscular Dystrophy
por: Kharraz, Yacine, et al.
Publicado: (2014) -
Fibrogenic Cell Plasticity Blunts Tissue Regeneration and Aggravates Muscular Dystrophy
por: Pessina, Patrizia, et al.
Publicado: (2015) -
Increase in decorin and biglycan in Duchenne Muscular Dystrophy: role of fibroblasts as cell source of these proteoglycans in the disease
por: Fadic, Ricardo, et al.
Publicado: (2006) -
Whole-body clearing, staining and screening of calcium deposits in the mdx mouse model of Duchenne muscular dystrophy
por: Bozycki, Lukasz, et al.
Publicado: (2018) -
PAI-1–regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy
por: Ardite, Esther, et al.
Publicado: (2012)