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Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells

Obesity is associated with an activated macrophage phenotype in multiple tissues that contributes to tissue inflammation and metabolic disease. To evaluate the mechanisms by which obesity potentiates myeloid activation, we evaluated the hypothesis that obesity activates myeloid cell production from...

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Detalles Bibliográficos
Autores principales: Singer, Kanakadurga, DelProposto, Jennifer, Lee Morris, David, Zamarron, Brian, Mergian, Taleen, Maley, Nidhi, Cho, Kae Won, Geletka, Lynn, Subbaiah, Perla, Muir, Lindsey, Martinez-Santibanez, Gabriel, Nien-Kai Lumeng, Carey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142398/
https://www.ncbi.nlm.nih.gov/pubmed/25161889
http://dx.doi.org/10.1016/j.molmet.2014.06.005