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Epigenetic Impacts of Ascorbate on Human Metastatic Melanoma Cells

In recent years, increasing evidence has emerged demonstrating that high-dose ascorbate bears cytotoxic effects on cancer cells in vitro and in vivo, making ascorbate a pro-oxidative drug that catalyzes hydrogen peroxide production in tissues instead of acting as a radical scavenger. This anticancer...

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Detalles Bibliográficos
Autores principales: Venturelli, Sascha, Sinnberg, Tobias W., Berger, Alexander, Noor, Seema, Levesque, Mitchell Paul, Böcker, Alexander, Niessner, Heike, Lauer, Ulrich M., Bitzer, Michael, Garbe, Claus, Busch, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142417/
https://www.ncbi.nlm.nih.gov/pubmed/25202679
http://dx.doi.org/10.3389/fonc.2014.00227