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Crystal structure of Clostridium acetobutylicum aspartate kinase (CaAk): An important allosteric enzyme for amino acids production

Aspartate kinase (AK) is an enzyme which is tightly regulated through feedback control and responsible for the synthesis of 4-phospho-l-aspartate from l-aspartate. This intermediate step is at an important branch point where one path leads to the synthesis of lysine and the other to threonine, methi...

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Detalles Bibliográficos
Autores principales: Manjasetty, Babu A., Chance, Mark R., Burley, Stephen K., Panjikar, Santosh, Almo, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142519/
https://www.ncbi.nlm.nih.gov/pubmed/25170437
http://dx.doi.org/10.1016/j.btre.2014.06.009