Ectodomain shedding of TβRIII is required for TβRIII-mediated suppression of TGF-β signaling and breast cancer migration and invasion

The type III transforming growth factor β (TGF-β) receptor (TβRIII), also known as betaglycan, is the most abundantly expressed TGF-β receptor. TβRIII suppresses breast cancer progression by inhibiting migration, invasion, metastasis, and angiogenesis. TβRIII binds TGF-β ligands, with membrane-bound...

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Detalles Bibliográficos
Autores principales: Elderbroom, Jennifer L., Huang, Jennifer J., Gatza, Catherine E., Chen, Jian, How, Tam, Starr, Mark, Nixon, Andrew B., Blobe, Gerard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142606/
https://www.ncbi.nlm.nih.gov/pubmed/24966170
http://dx.doi.org/10.1091/mbc.E13-09-0524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142606/
https://www.ncbi.nlm.nih.gov/pubmed/24966170
http://dx.doi.org/10.1091/mbc.E13-09-0524

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