Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells

The filtration unit of the kidney is the glomerulus, a capillary network supported by mesangial cells and extracellular matrix (ECM). Glomerular function is compromised in diabetic nephropathy (DN) by uncontrolled buildup of ECM, especially type IV collagen, which progressively occludes the capillar...

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Detalles Bibliográficos
Autores principales: Miller, Charles G., Pozzi, Ambra, Zent, Roy, Schwarzbauer, Jean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142608/
https://www.ncbi.nlm.nih.gov/pubmed/24943838
http://dx.doi.org/10.1091/mbc.E14-03-0800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142608/
https://www.ncbi.nlm.nih.gov/pubmed/24943838
http://dx.doi.org/10.1091/mbc.E14-03-0800

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