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Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells
The filtration unit of the kidney is the glomerulus, a capillary network supported by mesangial cells and extracellular matrix (ECM). Glomerular function is compromised in diabetic nephropathy (DN) by uncontrolled buildup of ECM, especially type IV collagen, which progressively occludes the capillar...
Autores principales: | Miller, Charles G., Pozzi, Ambra, Zent, Roy, Schwarzbauer, Jean E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142608/ https://www.ncbi.nlm.nih.gov/pubmed/24943838 http://dx.doi.org/10.1091/mbc.E14-03-0800 |
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