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Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation

The advent of genome-wide RNA interference (RNAi)–based screens puts us in the position to identify genes for all functions human cells carry out. However, for many functions, assay complexity and cost make genome-scale knockdown experiments impossible. Methods to predict genes required for cell fun...

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Detalles Bibliográficos
Autores principales: Hériché, Jean-Karim, Lees, Jon G., Morilla, Ian, Walter, Thomas, Petrova, Boryana, Roberti, M. Julia, Hossain, M. Julius, Adler, Priit, Fernández, José M., Krallinger, Martin, Haering, Christian H., Vilo, Jaak, Valencia, Alfonso, Ranea, Juan A., Orengo, Christine, Ellenberg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142622/
https://www.ncbi.nlm.nih.gov/pubmed/24943848
http://dx.doi.org/10.1091/mbc.E13-04-0221