In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice

Oxidative stress contributes to the progression of acute liver failure (ALF). Transcription factor nuclear factor-erythroid 2-related factor (Nrf2) serves as an endogenous regulator by which cells combat oxidative stress. We have investigated liver damage and the balance between death and survival s...

Descripción completa

Detalles Bibliográficos
Autores principales: González-Rodríguez, Águeda, Reibert, Bjorn, Amann, Thomas, Constien, Rainier, Rondinone, Cristina M., Valverde, Ángela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142729/
https://www.ncbi.nlm.nih.gov/pubmed/24997191
http://dx.doi.org/10.1242/dmm.015537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142729/
https://www.ncbi.nlm.nih.gov/pubmed/24997191
http://dx.doi.org/10.1242/dmm.015537

Ejemplares similares