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Synthesis and bioactivity of analogues of the marine antibiotic tropodithietic acid

Tropodithietic acid (TDA) is a structurally unique sulfur-containing antibiotic from the Roseobacter clade bacterium Phaeobacter inhibens DSM 17395 and a few other related species. We have synthesised several structural analogues of TDA and used them in bioactivity tests against Staphylococcus aureu...

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Detalles Bibliográficos
Autores principales: Rabe, Patrick, Klapschinski, Tim A, Brock, Nelson L, Citron, Christian A, D’Alvise, Paul, Gram, Lone, Dickschat, Jeroen S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142847/
https://www.ncbi.nlm.nih.gov/pubmed/25161739
http://dx.doi.org/10.3762/bjoc.10.188