One-pot stereoselective synthesis of α,β-differentiated diamino esters via the sequence of aminochlorination, aziridination and intermolecular S(N)2 reaction

We report here an efficient one-pot method for the synthesis of α,β-differentiated diamino esters directly from cinnamate esters using N,N-dichloro-p-toluenesulfonamide and benzylamine as nitrogen sources. The key transformations include a Cu-catalyzed aminohalogenation and aziridination, followed b...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Yiwen, Qian, Ping, Cao, Chenhui, Mei, Haibo, Han, Jianlin, Li, Guigen, Pan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142878/
https://www.ncbi.nlm.nih.gov/pubmed/25161740
http://dx.doi.org/10.3762/bjoc.10.189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142878/
https://www.ncbi.nlm.nih.gov/pubmed/25161740
http://dx.doi.org/10.3762/bjoc.10.189

Ejemplares similares