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The Study of DNA Methylation of bax Gene Promoter in Breast and Colorectal Carcinoma Cell Lines

BACKGROUND: The Bcl-2 protein family members have known as essential controllersof mitochondrial pathway of apoptosis. Bax has been implicated as potential tumor suppressor in certain solid tumors such as breast and colorectal carcinoma. DNA methylation of promoter associated CpG islands has known a...

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Detalles Bibliográficos
Autores principales: Alipour, Mohsen, Zargar, Seyed Jalal, Safarian, Shahrokh, Fouladdel, Shamileh, Azizi, Ebrahim, Jafargholizadeh, Naser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Research Center, Shahid Beheshti University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142912/
https://www.ncbi.nlm.nih.gov/pubmed/25250112