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Studies toward the Development of Antiproliferative Neoclerodanes from Salvinorin A

[Image: see text] The success rate for central nervous system (CNS) drug candidates in the clinic is relatively low compared to the industry average across other therapeutic areas. Penetration through the blood–brain barrier (BBB) to reach the therapeutic target is a major obstacle in development. T...

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Detalles Bibliográficos
Autores principales: Vasiljevik, Tamara, Groer, Chad E., Lehner, Kurt, Navarro, Hernan, Prisinzano, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143179/
https://www.ncbi.nlm.nih.gov/pubmed/25075762
http://dx.doi.org/10.1021/np5002048