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Studies toward the Development of Antiproliferative Neoclerodanes from Salvinorin A
[Image: see text] The success rate for central nervous system (CNS) drug candidates in the clinic is relatively low compared to the industry average across other therapeutic areas. Penetration through the blood–brain barrier (BBB) to reach the therapeutic target is a major obstacle in development. T...
Autores principales: | Vasiljevik, Tamara, Groer, Chad E., Lehner, Kurt, Navarro, Hernan, Prisinzano, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society and American
Society of Pharmacognosy
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143179/ https://www.ncbi.nlm.nih.gov/pubmed/25075762 http://dx.doi.org/10.1021/np5002048 |
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