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Inhibition and promotion of tumor growth with adeno-associated virus carcinoembryonic antigen vaccine and Toll like receptor agonists

Carcinoembryonic antigen (CEA) is a cancer vaccines target. Several feature of recombinant adeno-associated virus (rAAV) are attractive for vaccine applications. Combining other viral vector vaccines with Toll like receptor (TLR) agonists enhances antitumor immunity. Wild-type and CEA transgenic (Tg...

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Detalles Bibliográficos
Autores principales: Triozzi, Pierre L., Aldrich, Wayne, Ponnazhagan, Selvarangan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143190/
https://www.ncbi.nlm.nih.gov/pubmed/21869824
http://dx.doi.org/10.1038/cgt.2011.54