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Elevated Levels of FMR1 mRNA in Granulosa Cells Are Associated with Low Ovarian Reserve in FMR1 Premutation Carriers

AIM: To assess the role of mRNA accumulation in granulosa cells as the cause of low ovarian response among FMR1 premutation carriers undergoing pre-implantation genetic diagnosis (PGD). DESIGN: Case control study in an academic IVF unit. Twenty-one consecutive FMR1 premutation carriers and 15 contro...

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Detalles Bibliográficos
Autores principales: Elizur, Shai E., Lebovitz, Oshrit, Derech-Haim, Sanaz, Dratviman-Storobinsky, Olga, Feldman, Baruch, Dor, Jehoshua, Orvieto, Raoul, Cohen, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143194/
https://www.ncbi.nlm.nih.gov/pubmed/25153074
http://dx.doi.org/10.1371/journal.pone.0105121