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ERKs and mitochondria-related pathways are essential for glycyrrhizic acid-mediated neuroprotection against glutamate-induced toxicity in differentiated PC12 cells

The present study focuses on the neuroprotective effect of glycyrrhizic acid (GA, a major compound separated from Glycyrrhiza Radix, which is a crude Chinese traditional drug) against glutamate-induced cytotoxicity in differentiated PC12 (DPC12) cells. The results showed that GA treatment improved c...

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Detalles Bibliográficos
Autores principales: Wang, D., Guo, T.Q., Wang, Z.Y., Lu, J.H., Liu, D.P., Meng, Q.F., Xie, J., Zhang, X.L., Liu, Y., Teng, L.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143205/
https://www.ncbi.nlm.nih.gov/pubmed/25075574
http://dx.doi.org/10.1590/1414-431X20143760