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Inhibition of PKC-dependent extracellular Ca(2+) entry contributes to the depression of contractile activity in long-term pressure-overloaded endothelium-denuded rat aortas

We examined the contractile responsiveness of rat thoracic aortas under pressure overload after long-term suprarenal abdominal aortic coarctation (lt-Srac). Endothelium-dependent angiotensin II (ANG II) type 2 receptor (AT(2)R)-mediated depression of contractions to ANG II has been reported in short...

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Detalles Bibliográficos
Autores principales: Padilla, J., López, R.M., López, P., Castillo, M.C., Querejeta, E., Ruiz, A., Castillo, E.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143207/
https://www.ncbi.nlm.nih.gov/pubmed/25098618
http://dx.doi.org/10.1590/1414-431X20143073