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ALKBH4 Depletion in Mice Leads to Spermatogenic Defects

ALKBH4, an AlkB homologue in the 2-oxoglutarate and Fe(2+) dependent hydroxylase family, has previously been shown to regulate the level of monomethylated lysine-84 in actin and thereby indirectly influences the ability of non-muscular myosin II to bind actin filaments. ALKBH4 modulates fundamental...

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Detalles Bibliográficos
Autores principales: Nilsen, Anja, Fusser, Markus, Greggains, Gareth, Fedorcsak, Peter, Klungland, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143218/
https://www.ncbi.nlm.nih.gov/pubmed/25153837
http://dx.doi.org/10.1371/journal.pone.0105113