Global hypomethylation and promoter methylation in small intestinal neuroendocrine tumors: An in vivo and in vitro study

Aberrant DNA methylation is a feature of human cancer affecting gene expression and tumor phenotype. Here, we quantified promoter methylation of candidate genes and global methylation in 44 small intestinal-neuroendocrine tumors (SI-NETs) from 33 patients by pyrosequencing. Findings were compared wi...

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Detalles Bibliográficos
Autores principales: Fotouhi, Omid, Adel Fahmideh, Maral, Kjellman, Magnus, Sulaiman, Luqman, Höög, Anders, Zedenius, Jan, Hashemi, Jamileh, Larsson, Catharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143414/
https://www.ncbi.nlm.nih.gov/pubmed/24762809
http://dx.doi.org/10.4161/epi.28936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143414/
https://www.ncbi.nlm.nih.gov/pubmed/24762809
http://dx.doi.org/10.4161/epi.28936

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