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Pyrroloquinoline Quinone Induces Cancer Cell Apoptosis via Mitochondrial-Dependent Pathway and Down-Regulating Cellular Bcl-2 Protein Expression

Pyrroloquinoline quinone (PQQ) has been reported as a promising agent that might contribute to tumor cell apoptosis and death, yet little is known on its mechanisms. In current study, the effect of PQQ on cell proliferation and mitochondrial-dependent apoptosis were examined in 3 solid tumor cell li...

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Detalles Bibliográficos
Autores principales: Min, Zhihui, Wang, Lingyan, Jin, Jianjun, Wang, Xiangdong, Zhu, Bijun, Chen, Hao, Cheng, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143536/
https://www.ncbi.nlm.nih.gov/pubmed/25161699
http://dx.doi.org/10.7150/jca.9002