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Transient dynamics of Aβ contribute to toxicity in Alzheimer’s disease

The aggregation and deposition of the amyloid-β peptide (Aβ) in the brain has been linked with neuronal death, which progresses in the diagnostic and pathological signs of Alzheimer’s disease (AD). The transition of an unstructured monomeric peptide into self-assembled and more structured aggregates...

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Detalles Bibliográficos
Autores principales: Hubin, E., van Nuland, N. A. J., Broersen, K., Pauwels, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143600/
https://www.ncbi.nlm.nih.gov/pubmed/24803005
http://dx.doi.org/10.1007/s00018-014-1634-z