Lack of Neuroprotective Effect of Celastrol Under Conditions of Proteasome Inhibition by Lactacystin in In Vitro and In Vivo Studies: Implications for Parkinson’s Disease

A number of studies suggest that the ubiquitin–proteasome system (UPS) impairment may underlie neuronal death in Parkinson’s disease. Celastrol is a neuroprotective agent with anti-inflammatory and antioxidant properties. The aim of this study was to determine whether celastrol may exert neuroprotec...

Descripción completa

Detalles Bibliográficos
Autores principales: Konieczny, Jolanta, Jantas, Danuta, Lenda, Tomasz, Domin, Helena, Czarnecka, Anna, Kuter, Katarzyna, Śmiałowska, Maria, Lasoń, Władysław, Lorenc-Koci, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143605/
https://www.ncbi.nlm.nih.gov/pubmed/24842651
http://dx.doi.org/10.1007/s12640-014-9477-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143605/
https://www.ncbi.nlm.nih.gov/pubmed/24842651
http://dx.doi.org/10.1007/s12640-014-9477-9

Ejemplares similares