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Comparison of multilevel modeling and the family-based association test for identifying genetic variants associated with systolic and diastolic blood pressure using Genetic Analysis Workshop 18 simulated data

Identifying genetic variants associated with complex diseases is an important task in genetic research. Although association studies based on unrelated individuals (ie, case-control genome-wide association studies) have successfully identified common single-nucleotide polymorphisms for many complex...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Yu, Robert, Shete, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143633/
https://www.ncbi.nlm.nih.gov/pubmed/25519380
http://dx.doi.org/10.1186/1753-6561-8-S1-S30