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Application of noncollapsing methods to the gene-based association test: a comparison study using Genetic Analysis Workshop 18 data
Rare variants have been proposed to play a significant role in the onset and development of common diseases. However, traditional analysis methods have difficulties in detecting association signals for rare causal variants because of a lack of statistical power. We propose a two-stage, gene-based me...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143635/ https://www.ncbi.nlm.nih.gov/pubmed/25519333 http://dx.doi.org/10.1186/1753-6561-8-S1-S53 |