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Single-marker and multi-marker mixed models for polygenic score analysis in family-based data
Genome-wide association studies have proven successful but they remain underpowered for detecting variants of weaker effect. Alternative methods propose to test for association by using an aggregate score that combines the effects of the most associated variants. The set of variants that are to be a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143662/ https://www.ncbi.nlm.nih.gov/pubmed/25519337 http://dx.doi.org/10.1186/1753-6561-8-S1-S63 |