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Single-marker and multi-marker mixed models for polygenic score analysis in family-based data

Genome-wide association studies have proven successful but they remain underpowered for detecting variants of weaker effect. Alternative methods propose to test for association by using an aggregate score that combines the effects of the most associated variants. The set of variants that are to be a...

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Detalles Bibliográficos
Autores principales:	Bohossian, Nora, Saad, Mohamad, Legarra, Andrés, Martinez, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143662/ https://www.ncbi.nlm.nih.gov/pubmed/25519337 http://dx.doi.org/10.1186/1753-6561-8-S1-S63

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