Application of family-based tests of association for rare variants to pathways

Pathway analysis approaches for sequence data typically either operate in a single stage (all variants within all genes in the pathway are combined into a single, very large set of variants that can then be analyzed using standard "gene-based" test statistics) or in 2-stages (gene-based p...

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Detalles Bibliográficos
Autores principales: Greco, Brian, Luedtke, Alexander, Hainline, Allison, Alvarez, Carolina, Beck, Andrew, Tintle, Nathan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143675/
https://www.ncbi.nlm.nih.gov/pubmed/25519359
http://dx.doi.org/10.1186/1753-6561-8-S1-S105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143675/
https://www.ncbi.nlm.nih.gov/pubmed/25519359
http://dx.doi.org/10.1186/1753-6561-8-S1-S105

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