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Validation of a novel procedure for quantification of the formation of phosphoramide mustard by individuals treated with cyclophosphamide
PURPOSE: Use of the patient’s body surface area (mg m(−2)) as a basis for dosing does not take individual variation in metabolic capacity and rate of clearance into account. Here, we evaluated a novel approach for individual monitoring of short-lived cytotoxic agents formed from cytostatic drugs suc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143677/ https://www.ncbi.nlm.nih.gov/pubmed/25053385 http://dx.doi.org/10.1007/s00280-014-2524-7 |