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Validation of a novel procedure for quantification of the formation of phosphoramide mustard by individuals treated with cyclophosphamide

PURPOSE: Use of the patient’s body surface area (mg m(−2)) as a basis for dosing does not take individual variation in metabolic capacity and rate of clearance into account. Here, we evaluated a novel approach for individual monitoring of short-lived cytotoxic agents formed from cytostatic drugs suc...

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Detalles Bibliográficos
Autores principales: von Stedingk, Hans, Xie, Hanjing, Hatschek, Thomas, Foukakis, Theodoros, Rydén, Andreas, Bergh, Jonas, Rydberg, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143677/
https://www.ncbi.nlm.nih.gov/pubmed/25053385
http://dx.doi.org/10.1007/s00280-014-2524-7